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Multiple Choice

Gout is more common in which sex?

Gout occurs when uric acid builds up and crystallizes in joints. Sex hormones influence uric acid handling in the kidneys: estrogen helps clear urate, so premenopausal women typically have lower uric acid levels and a lower gout risk. Men, on average, have higher serum urate and a higher tendency to develop hyperuricemia. After menopause, women's risk increases as estrogen protection wanes, but overall the frequency of gout remains greater in men. So, the groups most commonly affected are men, especially in middle age; women tend to develop gout later, if at all.

Gout occurs when uric acid builds up and crystallizes in joints. Sex hormones influence uric acid handling in the kidneys: estrogen helps clear urate, so premenopausal women typically have lower uric acid levels and a lower gout risk. Men, on average, have higher serum urate and a higher tendency to develop hyperuricemia. After menopause, women's risk increases as estrogen protection wanes, but overall the frequency of gout remains greater in men.

So, the groups most commonly affected are men, especially in middle age; women tend to develop gout later, if at all.